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Clarithromycin is a broad spectrum antibiotic belongs to macrolide group, is used for treating bacterial infections such as pharyngitis, tonsillitis, acute maxillary sinusitis, acute bacterial exacerbation of chronic bronchitis, pneumonia (especially atypical pneumonias associated with Chlamydia pneumoniae, or TWAR), skin and skin structure infections, and HIV and AIDS patients to prevent and treat, disseminated Mycobacterium avium complex (MAC). In addition, Clarithromycin is sometimes used to treat Legionellosis.
Clarithromycin is available under several brand names, for example Biaxin, Klaricid, Klabax, Claripen, Claridar, Fromilid, Clacid and infex.
Generic Name: Clarithromycin
Available As: 250mg, 500mg tablet form
Clarithromycin Drug Class and Mechanism
Biaxin is a macrolide antibiotic. It works by stopping the growth of or killing sensitive bacteria by reducing the production of important proteins needed by the bacteria to survive. is used for treating bacterial infections such as
- pharyngitis,
- tonsillitis,
- acute maxillary sinusitis,
- acute bacterial exacerbation of chronic bronchitis (AECB),
- pneumonia (especially atypical pneumonias associated with Chlamydia pneumoniae, or TWAR),
- Skin and skin structure infections, and
- HIV and AIDS patients to prevent and treat,
- disseminated Mycobacterium avium complex (MAC).
- In addition, Clarithromycin is sometimes used to treat Legionellosis.
Important information before starting prescription drug Clarithromycin treatment?
- Take all of the Clarithromycin medication that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated.
- Do not take Clarithromycin if you are taking cisapride (Propulsid), pimozide (Orap), or terfenadine (Seldane). These medicines can interact, possibly leading to a dangerous irregular heartbeat pattern.
- Do not take Clarithromycin (Biaxin) if you are taking cisapride (Propulsid), pimozide (Orap), or terfenadine (Seldane). These medicines can interact, possibly leading to a dangerous irregular heartbeat pattern.
- Before taking Clarithromycin (Biaxin), tell your doctor if you have liver or kidney disease. You may not be able to take Biaxin, or you may require a lower dose and special monitoring during therapy.
- Clarithromycin (Biaxin) is in the FDA pregnancy category C. This means that it is not known whether Biaxin will harm an unborn baby. Do not take Clarithromycin without first talking to your doctor if you are pregnant.
- It is not known whether Clarithromycin passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.
What is Clarithromycin?
- Clarithromycin in Biaxin, Klaricid, Klabax, Claripen, Claridar, Fromilid, Clacid and infex is a class of drugs called macrolide antibiotics. Clarithromycin fights bacteria in your body.
- Clarithromycin is used to treat many different types of bacterial infections, such as bronchitis, pneumonia, sinusitis, tonsillitis, skin infections, and stomach ulcers caused by bacteria.
- Clarithromycin may also be used for purposes other than those listed in this medication guide.
Do not use prescription (Biaxin) medication if:
- If y ou are allergic to any ingredient in Biaxin or any other macrolide (e.g., erythromycin);
- If you are taking cisapride, cyclosporine, dofetilide, eletriptan, ergot alkaloids (e.g., ergotamine, dihydroergotamine), H1 antagonists (e.g., terfenadine, astemizole), pimozide, QT-prolonging agents (e.g., quinidine, sotalol, thioridazine), quinolones (e.g., ciprofloxacin), or sumatriptan.
- Contact your doctor or health care provider right away if any of these apply to you.
Clarithromycin Important information:
- Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
- Biaxin only works against bacteria; it does not treat viral infections (e.g., the common cold).
- Long-term or repeated use of Biaxin may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
- Be sure to use Biaxin for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
- Lab tests, including complete blood counts, may be performed while you use Biaxin. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Pregnancy and breast-feeding: This medicine has been shown to cause harm to the fetus. Biaxin is not recommended for use during pregnancy except when no other antibiotics can be used. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Biaxin while you are pregnant. It is not known if Biaxin is found in breast milk. If you are or will be breast-feeding while you use Biaxin, check with your doctor. Discuss any possible risks to your baby.
Clarithromycin dosages?
- Take Clarithromycin medication exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
- Take each dose with a full glass (8 ounces) of water.
- Clarithromycin can be taken with food or milk or on an empty stomach.
- Take extended release Clarithromycin Biaxin (Biaxin XL) with food.
- Clarithromycin is usually taken two times a day with the doses about 12 hours apart. Follow your doctor's instructions.
- Take all of the Clarithromycin that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated.
- Store Clarithromycin medication at room temperature away from moisture and heat. Do not refrigerate the suspension.
If you miss a dose of Clarithromycin?
- Take the missed dose as soon as you remember. However, if it is almost time for your next regularly scheduled dose, skip the missed dose and take the next one as directed.
- Do not take a double dose of this medication unless otherwise directed by your doctor.
What happens if I overdose Clarithromycin?
- Seek emergency medical attention.
- Symptoms of an Clarithromycin (Biaxin) overdose include nausea, vomiting, diarrhea, and abdominal discomfort.
Clarithromycin Possible Side Effects?
Check with your doctor if any of these most common side effects persist or become bothersome:
- abnormal taste; diarrhea; headache; indigestion; nausea; stomach discomfort; vomiting.
Seek medical attention right away if any of these severe side effects occur:
- severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; confusion; decreased urination; depression; emotional or mood changes; hallucinations; nightmares; severe diarrhea; severe stomach pain/cramps; trouble sleeping.
- If you experience any of the following serious side effects, stop taking Biaxin and seek emergency medical attention:
- an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives), or
- liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue).
- Other, less serious side effects may be more likely to occur. Continue to take Biaxin and talk to your doctor if you experience
- nausea, vomiting, diarrhea, or abdominal pain;
- dizziness, fatigue, or headache;
- a rash; or
- vaginal yeast infection.
- Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
Clarithromycin More Information
Clarithromycin in Klaricid, Klabax, Claripen, Claridar, Fromilid, Clacid and infex is to be used only by the patient for whom it is prescribed. Do not share it with other people.
What other drugs will affect Clarithromycin?
Clarithromycin may cause dangerous side effects when taken with the following drugs:
- antihistamines such as terfenadine (Seldane) and astemizole (Hismanal);
- seizure medications such as carbamazepine (Tegretol), phenytoin (Dilantin), and valproic acid (Depakote, Depakene);
- asthma medications such as theophylline (Theo-Dur, Theolair, Theochron, others);
- anticoagulants (blood thinners) such as warfarin (Coumadin);
- heart medications for irregular heartbeats, such as digoxin (Lanoxin) and disopyramide (Norpace);
- Ergotamine (ergostat) or dihydroergotamine (D.H.E.);
- HMG-COA Reductase Inhibitors such as atorvastin (Lipitor), simvastatin (Zocor), lovastatin (Mevacor) and others;
- Benzodiazepines such as diazepam (Valium), triazolam (Halcion), alprazolam (Xanax) and others;
- sildenafil (Viagra) or vardenafil (Levitra); or
- other antibiotics. Do not use other antibiotics unless they are prescribed by your doctor.
- Do not take Biaxin without first talking to your doctor if you are taking any of the medicines listed above.
- Drugs other than those listed here may also interact with Biaxin. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.
Where can I get more information on Clarithromycin drug ?
Your pharmacist has additional information about Clarithromycin written for health professionals that you may read.
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